There is no better example of “failure to rescue” than the opioid crisis – it is exploding. The public, our youth, our families, and our organizations are under attack. Most of us are unaware of the explosion of opioid overdoses until they hurt someone close to us. It is up to our healthcare and public safety leaders to act now. Please join us as we address the magnitude of the problem – the who, what, where, and why. Help us identify ways our patient safety community leaders can provide solutions through leadership, practices, and technologies.